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Article

Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study.

Journal of medical genetics - 1 Oct 2006

Guo Yan-fang, Xiong Dong-hai, Shen Hui, Zhao Lan-juan, Xiao Peng, Guo Yan, Wang Wei, Yang Tie-lin, Recker Robert R, Deng Hong-wen

Abstract excerpt

BACKGROUND: The low-density lipoprotein receptor-related protein 5 (LRP5) gene, essential for glucose and cholesterol metabolism, may have a role in the aetiology of obesity, an important risk factor for diabetes. PARTICIPANTS AND METHODS: To investigate the association between LRP5 polymorphisms and obesity, 27 single-nucleotide polymorphisms (SNPs), spacing about 5 kb apart on average and covering the full...

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Source

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Identifiers

PMID: 16723389
DOI: 10.1136/jmg.2006.041715
PMCID: PMC1829485

Genes

LRP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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