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Article

Effects of variation at the ALDH2 locus on alcohol metabolism, sensitivity, consumption, and dependence in Europeans.

Alcoholism, clinical and experimental research - 1 Jul 2006

Dickson Peter A, James Michael R, Heath Andrew C, Montgomery Grant W, Martin Nicholas G, Whitfield John B, Birley Andrew J

Abstract excerpt

BACKGROUND: The low-activity variant of the aldehyde dehydrogenase 2 (ALDH2) gene found in East Asian populations leads to the alcohol flush reaction and reduces alcohol consumption and risk of alcohol dependence (AD). We have tested whether other polymorphisms in the ALDH2 gene have similar effects in people of European ancestry. METHODS: Serial measurements of blood and breath alcohol, subjective intoxication,...

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Source

Identifiers

PMID: 16792555
DOI: 10.1111/j.1530-0277.2006.00128.x

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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