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Article

Inverse correlation of genetic risk score with age at onset in bout-onset and progressive-onset multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Oct 2015

Sorosina Melissa, Esposito Federica, Guaschino Clara, Clarelli Ferdinando, Barizzone Nadia, Osiceanu Ana Maria, Brambilla Paola, Mascia Elisabetta, Cavalla Paola, Gallo Paolo, Martinelli Vittorio, Leone Maurizio, Comi Giancarlo, D'Alfonso Sandra, Martinelli Boneschi Filippo

Abstract excerpt

We correlated the weighted genetic risk score measured using 107 established susceptibility variants for multiple sclerosis (MS) with the age at onset in bout-onset (BOMS, n=906) and progressive-onset MS Italian patients (PrMS) (n=544). We observed an opposite relationship in the two disease cour...

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PMID: 25533292
DOI: 10.1177/1352458514561910

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25533292-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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