Article
Estimating the proportion of variation in susceptibility to multiple sclerosis captured by common SNPs.
Scientific reports - 1 Jan 2012
Watson Corey T, Disanto Giulio, Breden Felix, Giovannoni Gavin, Ramagopalan Sreeram V
Abstract excerpt
Multiple sclerosis (MS) is a complex disease with underlying genetic and environmental factors. Although the contribution of alleles within the major histocompatibility complex (MHC) are known to exert strong effects on MS risk, much remains to be learned about the contributions of loci with more modest effects identified by genome-wide association studies (GWASs), as well as loci that remain undiscovered. We use...
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