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Article

Metastatic melanoma of unknown primary resembles the genotype of cutaneous melanomas.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jan 2014

Egberts F, Bergner I, Krüger S, Haag J, Behrens H M, Hauschild A, Röcken C

Abstract excerpt

BACKGROUND: Although 90% of all melanomas are of cutaneous origin, some patients present with melanoma metastases of unknown origin (MUP). Commonly, in these patients an extensive search for the primary tumor is carried out. In the past, genetic analyses have shown substantial differences in pathogenetic mutations among cutaneous, acral and mucosal melanomas. The aim of this study was to assess the mutational...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24276025
DOI: 10.1093/annonc/mdt411

Genes

BRAF
NRAS
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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