Article
Genetic concordance in melanoma: insights from primary tumors and their matched distant metastases.
Melanoma research - 1 Jun 2025
Kerkour Thamila, Meijers Ruud W J, Hollestein Loes M, Jansen Anne M L, Haanappel Ayla, Atmodimedjo Peggy, Blokx Willeke A M, van Brakel Bas, Nijsten Tamar E C, Mooyaart Antien L
Abstract excerpt
Melanoma metastasis poses a significant challenge due to its aggressive nature and increasing incidence. Confirming the clonal relationship between the primary melanoma and its metastasis is essential to developing reliable prediction models. Here, we compared the genetic profile of primary melanoma and matched metastasis to assess their genetic clonal relationship. Using a targeted sequencing panel encompassing...
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