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Article

Concordance of somatic mutational profile in multiple primary melanomas.

Pigment cell & melanoma research - 1 Sept 2018

Adler Nikki R, McLean Catriona A, Wolfe Rory, Kelly John W, McArthur Grant A, Haydon Andrew, Tra Thien, Cummings Nicholas, Mar Victoria J

Abstract excerpt

This study aimed to determine the frequency and concordance of BRAF and NRAS mutation in tumours arising in patients with multiple primary melanoma (MPM). Patients with MPM managed at one of three tertiary referral centres in Melbourne, Australia, from 2010 to 2015 were included. Incident and subsequent melanomas underwent mutation testing. Cohen's kappa (κ) coefficient assessed agreement between incident and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29603877
DOI: 10.1111/pcmr.12702

Genes

BRAF
NRAS

Provenance

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