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Article

Molecular characterization and patient outcome of melanoma nodal metastases and an unknown primary site.

Annals of surgical oncology - 1 Dec 2014

Gos Aleksandra, Jurkowska Monika, van Akkooi Alexander, Robert Caroline, Kosela-Paterczyk Hanna, Koljenović Senada, Kamsukom Nyam, Michej Wanda, Jeziorski Arkadiusz, Pluta Piotr, Verhoef Cornelis, Siedlecki Janusz A, Eggermont Alexander M M, Rutkowski Piotr

Abstract excerpt

BACKGROUND: Melanoma of unknown primary site (MUP) is not a completely understood entity with nodal metastases as the most common first clinical manifestation. The aim of this multicentric study was to assess frequency and type of oncogenic BRAF/NRAS/KIT mutations in MUP with clinically detected nodal metastases in relation to clinicopathologic features and outcome. MATERIALS AND METHODS: We analyzed series of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24866436
DOI: 10.1245/s10434-014-3799-y
PMCID: PMC4218979

Genes

BRAF
NRAS
KIT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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