Effect of BDNF Val66Met polymorphism on digital working memory and spatial localization in a healthy Chinese Han population.

doi:10.1007/s12031-009-9205-8

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Article

Effect of BDNF Val66Met polymorphism on digital working memory and spatial localization in a healthy Chinese Han population.

Journal of molecular neuroscience : MN - 1 Jul 2009

Gong Pingyuan, Zheng Anyun, Chen Dongmei, Ge Wanhua, Lv Changchao, Zhang Kejin, Gao Xiaocai, Zhang Fuchang

Abstract excerpt

Cognitive abilities are complex human traits influenced by genetic factors. Brain-derived neurotrophic factor (BDNF), a unique polypeptide growth factor, has an influence on the differentiation and survival of neurons in the nervous system. A single-nucleotide polymorphism (rs6265) in the human gene, resulting in a valine to methionine substitution in the pro-BDNF protein, was thought to associate with...

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PMID: 19424874
DOI: 10.1007/s12031-009-9205-8

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BDNF

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