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Article

The impact of hepatitis B virus precore/core gene carboxyl terminal mutations on viral biosynthesis and the host immune response.

The Journal of infectious diseases - 1 May 2014

Wu Jia-Feng, Ni Yen-Hsuan, Chen Huey-Ling, Hsu Hong-Yuan, Chang Mei-Hwei

Abstract excerpt

BACKGROUND: We aimed to elucidate the impact of hepatitis B virus (HBV) precore/core gene mutations on spontaneous hepatitis B e antigen (HBeAg) seroconversion, HBV biosynthesis, and the human immune responses in chronic HBV-infected patients. METHODS: We analyzed the HBV precore/core gene sequences by cloning method in 33 chronic HBV-infected patients during the inflammatory phase before spontaneous HBeAg...

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Source

Identifiers

PMID: 24273041
DOI: 10.1093/infdis/jit638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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