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Article

Clinical significance and evolution of core promoter and precore mutations in HBeAg-positive patients with HBV genotype B and C: a longitudinal study.

Liver international : official journal of the International Association for the Study of the Liver - 1 Aug 2007

Chen Chien-Hung, Lee Chuan-Mo, Hung Chao-Hung, Hu Tsung-Hui, Wang Jing-Houng, Wang Jyh-Chwan, Lu Sheng-Nan, Changchien Chi-Sin

Abstract excerpt

BACKGROUND/AIMS: The aims of this longitudinal study were to investigate whether the clinical outcome and evolution of core promoter and precore mutations were different during hepatitis B e antigen (HBeAg) seroconversion between hepatitis B virus (HBV) genotypes B and C in HBeAg-positive patients with chronic hepatitis B. PATIENTS AND METHODS: The core promoter and precore sequences were determined from serial...

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Identifiers

PMID: 17617124
DOI: 10.1111/j.1478-3231.2007.01505.x

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