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Article

A mutation in the canine gene encoding folliculin-interacting protein 2 (FNIP2) associated with a unique disruption in spinal cord myelination.

Glia - 1 Jan 2014

Pemberton Trevor J, Choi Sunju, Mayer Joshua A, Li Fang-Yuan, Gokey Nolan, Svaren John, Safra Noa, Bannasch Danika L, Sullivan Katrina, Breuhaus Babetta, Patel Pragna I, Duncan Ian D

Abstract excerpt

Novel mutations in myelin and myelin-associated genes have provided important information on oligodendrocytes and myelin and the effects of their disruption on the normal developmental process of myelination of the central nervous system (CNS). We report here a mutation in the folliculin-interacting protein 2 (FNIP2) gene in the Weimaraner dog that results in hypomyelination of the brain and a tract-specific...

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Identifiers

PMID: 24272703
DOI: 10.1002/glia.22582
PMCID: PMC4026025

Genes

FNIP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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