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Article

Rhabdoid morphology in gastrointestinal stromal tumours (GISTs) is associated with PDGFRA mutations but does not imply aggressive behaviour.

Histopathology - 1 Feb 2014

Schaefer Inga-Marie, Ströbel Philipp, Cameron Silke, Beham Alexander, Otto Claudia, Schildhaus Hans-Ulrich, Agaimy Abbas

Abstract excerpt

AIMS: Rhabdoid morphology resembling that of the aggressive paediatric rhabdoid tumours occurs in various malignancies usually lacking characteristic SMARCB1 (INI1) loss. Little is known about the clinicopathological and molecular characteristics of the rhabdoid phenotype in gastrointestinal stromal tumours (GISTs). METHODS AND RESULTS: Six gastric rhabdoid GISTs were examined by immunohistochemistry, KIT and...

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Share to Chromosomal Proteins, Non-Histone
Share to Comparative Genomic Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastrointestinal Stromal Tumors

Share to Neoplasm Invasiveness

Share to Proto-Oncogene Proteins c-kit

Share to Receptor, Platelet-Derived Growth Factor alpha

Share to SMARCB1 Protein

Share to Stomach Neoplasms

Source

Identifiers

PMID: 24266839
DOI: 10.1111/his.12265

Genes

PDGFRA
KIT
SMARCB1
SDHB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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