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Article

Molecular and clinicopathological features of KIT/PDGFRA wild-type gastrointestinal stromal tumors.

Cancer science - 1 Mar 2024

Nishida Toshirou, Naito Yoichi, Takahashi Tsuyoshi, Saito Takuro, Hisamori Shigeo, Manaka Dai, Ogawa Katsuhiro, Hirota Seiichi, Ichikawa Hitoshi

Abstract excerpt

Approximately 10% of gastrointestinal stromal tumors (GISTs) harbor reportedly no KIT and PDGFRA mutations (wild-type GISTs). The clinicopathological features and oncologic outcomes of wild-type GISTs based on molecular profiles are unknown. We recruited 35 wild-type GIST patients from the two registry studies of high-risk GISTs between 2012 and 2015 and primary GISTs between 2003 and 2014. Molecular profiling of...

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Identifiers

PMID: 38178783
DOI: 10.1111/cas.16058
PMCID: PMC10920999

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