Article
Molecular and morphological correlation in gastrointestinal stromal tumours (GISTs): an update and primer.
Journal of clinical pathology - 1 Sept 2016
Chetty Runjan, Serra Stefano
Abstract excerpt
Gastrointestinal stromal tumours (GISTs) are a commonly encountered tumour in routine practice. In the main, the morphology of spindle, epithelioid or mixed are well recognised along with mutations of c-kit However, there are other genes that are mutated resulting in characteristic clinicopathological correlations. GISTs harbouring platelet-derived growth factor receptor α (PDGFRα) gene mutations lead to a...
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