Article
Classification of gastrointestinal stromal tumor syndromes.
Endocrine-related cancer - 1 Feb 2018
Gopie Priya, Mei Lin, Faber Anthony C, Grossman Steven R, Smith Steven C, Boikos Sosipatros A
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, thought to derive from neoplastic outgrowth of the interstitial cells of Cajal. Building on recent advances in recognition, classification and diagnosis, the past two decades have seen a changing paradigm with molecular diagnostics and targeted therapies. KIT and PDGFRA mutations account for 85-90% of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.