Article
Genetic variation in immunoglobulin G receptor affects survival after lung transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Jul 2014
Ruttens D, Verleden S E, Goeminne P C, Vandermeulen E, Wauters E, Cox B, Vos R, Van Raemdonck D E, Lambrechts D, Vanaudenaerde B M, Verleden G M
Abstract excerpt
Chronic rejection remains the most important complication after lung transplantation (LTx). There is mounting evidence that both rheumatoid arthritis and chronic rejection share similar inflammatory mechanisms. As genetic variants in the FCGR2A gene that encodes the immunoglobulin gamma receptor (IgGR) have been identified in rheumatoid arthritis, we investigated the relationship between a genetic variant in the...
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