Article
The impact of interleukin 12B (1188A>C), interleukin 16 (-295T>C), and interleukin 18 (607C>A, 137G>C) gene polymorphisms on long-term renal transplant function and recipient outcomes.
Transplantation proceedings - 1 Jan 2000
Pawlus J, Sierocka A, Tejchman K, Ziętek Z, Romanowski M, Pawlik A, Sieńko J, Żukowski M, Ciechanowski K, Ostrowski M, Sulikowski T
Abstract excerpt
BACKGROUND: Inflammatory mediators play an important role in kidney graft outcome. The cytokine and chemokine gene polymorphisms are associated with variable production, activity, expression, or ligand-receptor affinity. Genetic variation in the DNA sequence of the interleukin 12B (IL12B), interl...
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