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Article

Polymorphisms of the CTLA4 gene and kidney transplant rejection in Korean patients.

Transplant immunology - 1 Oct 2010

Kim Hak-Jae, Jeong Kyung-Hwan, Lee Sang-Ho, Moon Joo-Young, Lee Tae-won, Kang Sun Woo, Park Suk Joo, Kim Yeong-Hoon, Chung Joo-Ho

Abstract excerpt

Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) is a member of the immunoglobulin superfamily. CTLA4, which binds to B7 molecules on antigen- presenting cells, is expressed on activated T cells, thereby delivering negative signals that down-regulate T-cell proliferation and cytokine production. Consequently, CTLA4 may be a good candidate gene to evaluate in kidney transplantation rejection. In this study, we...

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Source

Identifiers

PMID: 20940051
DOI: 10.1016/j.trim.2010.10.001

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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