A genetic variation in APE1 is associated with gastric cancer survival in a Chinese population.

doi:10.1111/j.1349-7006.2011.01959.x

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A genetic variation in APE1 is associated with gastric cancer survival in a Chinese population.

Cancer science - 1 Jul 2011

Zhao Qinghong, Wang Wei, Zhang Zhengdong, Wang Shizhi, Wang Meilin, Zhou Jianwei, Gong Weida, Tan Yongfei, Wang Baolin, Chen Guoyu

Abstract excerpt

Altered DNA repair can be associated with aggressive tumor biology and impact on survival of cancer patients. We investigated whether genetic variation of human apurinic/apyrimidinic (AP) endonuclease, a key multifunctional gene involved in the base excision repair pathway, would play a role in gastric cancer survival outcomes. We genotyped APE1 rs1760944 by the TaqMan method in 925 gastric cancer patients....

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PMID: 21615620
DOI: 10.1111/j.1349-7006.2011.01959.x

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