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Article

A genetic variant in the promoter of APE1 gene (-656 T>G) is associated with breast cancer risk and progression in a Chinese population.

Gene - 15 Nov 2013

Kang Huafeng, Dai Zhijun, Ma Xiaobin, Ma Li, Jin Yaofeng, Liu Xiaoxu, Wang Xijing

Abstract excerpt

BACKGROUND/AIMS: APE1 is an important DNA repair protein in the base excision repair pathway. Genetic variations in APE1 have been suggested to influence individuals' susceptibility to human malignancies. The present study was aimed to investigate the associations between two functional polymorphisms in APE1 (-656T>G and 1349T>G) and breast cancer risk. METHODS: We genotyped the two polymorphisms in a...

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Identifiers

PMID: 23994194
DOI: 10.1016/j.gene.2013.08.052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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