Article
APE1 polymorphisms are associated with colorectal cancer susceptibility in Chinese Hans.
World journal of gastroenterology - 14 Jul 2014
Zhang Shi-Heng, Wang Lin-Ang, Li Zheng, Peng Yu, Cun Yan-Ping, Dai Nan, Cheng Yi, Xiao He, Xiong Yan-Li, Wang Dong
Abstract excerpt
AIM: To study the association between four base excision repair gene polymorphisms and colorectal cancer risk in a Chinese population. METHODS: Two hundred forty-seven colorectal cancer (CRC) patients and three hundred cancer-free controls were enrolled in this study. Four polymorphisms (OGG1 Ser326Cys, APE1 Asp148Glu, -141T/G in the promoter region, and XRCC1 Arg399Gln) in components of the base excision repair...
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