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Article

The DNA repair gene APE1 T1349G polymorphism and risk of gastric cancer in a Chinese population.

PloS one - 1 Jan 2011

Gu Dongying, Wang Meilin, Wang Shizhi, Zhang Zhengdong, Chen Jinfei

Abstract excerpt

BACKGROUND: Apurinic/apyrimidinic endonuclease 1 (APE1) has a central role in the repair of apurinic apyrimidic sites through both its endonuclease and its phosphodiesterase activities. A common APE1 polymorphism, T1349G (rs3136820), was previously shown to be associated with the risk of cancers. OBJECTIVE: We hypothesized that the APE1 T1349G polymorphism is also associated with risk of gastric cancer. METHODS:...

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Identifiers

PMID: 22205985
DOI: 10.1371/journal.pone.0028971
PMCID: PMC3242764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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