Article
Association of the polymorphism of APE1 gene with the risk of prostate cancer in Chinese Han population.
Clinical laboratory - 1 Jan 2013
Jing Bao, Wang Juan, Chang Wen-Liang, Li Bo, Chen Jing, Niu Yuan-Jie
Abstract excerpt
BACKGROUND: DNA damage, caused by numerous carcinogens, contributes to the increased risk of different types of cancer. The base excision repair (BER) pathway including the apurinic/apyrimidic endonuclease (APE1, also known as APEX1) gene plays an important role in preventing the accumulation of DNA damage and maintaining genomic stability. The aim of the present study is to determine whether polymorphisms of...
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