Article
Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data.
Bioinformatics (Oxford, England) - 15 Jan 2014
Waszak Sebastian M, Kilpinen Helena, Gschwind Andreas R, Orioli Andrea, Raghav Sunil K, Witwicki Robert M, Migliavacca Eugenia, Yurovsky Alisa, Lappalainen Tuuli, Hernandez Nouria, Reymond Alexandre, Dermitzakis Emmanouil T, Deplancke Bart
Abstract excerpt
MOTIVATION: High-throughput sequencing technologies enable the genome-wide analysis of the impact of genetic variation on molecular phenotypes at unprecedented resolution. However, although powerful, these technologies can also introduce unexpected artifacts. RESULTS: We investigated the impact o...
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