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Article

Chromatin structure can introduce systematic biases in genome-wide analyses of Plasmodium falciparum

15 Sept 2022

Abstract excerpt

<h4>Background: </h4> The maintenance, regulation, and dynamics of heterochromatin in the human malaria parasite, Plasmodium falciparum, has drawn increasing attention due to its regulatory role in mutually exclusive virulence gene expression and the silencing of key developmental regulators. The advent of genome-wide analyses such as chromatin-immunoprecipitation followed by sequencing (ChIP-seq) has been...

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PMID: 37645349
DOI: 10.12688/openreseurope.14836.2

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