Article
Variability in the precore and core promoter region of the hepatitis B virus genome.
Journal of medical virology - 1 Mar 2014
Nordin Maria, Ingman Mikael, Lindqvist Beata, Kidd-Ljunggren Karin
Abstract excerpt
There is increasing evidence that hepatitis B virus (HBV) infections with different genotypes and subgenotypes differ in response to treatment and long-term prognosis. The differences emerge from variability within the genomes that leads to structural deviations at the pregenomic level and to changes at the translational level. Naturally occurring HBV strains covering the four major genotypes A-D were obtained...
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