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Article

Relationship of serological subtype, basic core promoter and precore mutations to genotypes/subgenotypes of hepatitis B virus.

Journal of medical virology - 1 Jan 2008

Kramvis Anna, Arakawa Kazuko, Yu Mimi C, Nogueira Ramon, Stram Daniel O, Kew Michael C

Abstract excerpt

Using phylogenetic analysis and pairwise comparison of 670 complete hepatitis B virus (HBV) genomes, we demonstrated that nucleotide divergence greater than 7.5% can be used to separate strains into genotypes A-H. Strains can be separated into subgenotypes when two criteria are met: nucleotide divergence of about 4% but less than 7.5% and good bootstrap support. There is a highly statistically significant...

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Identifiers

PMID: 18041043
DOI: 10.1002/jmv.21049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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