Article
T1764G1766 core promoter double mutants are restricted to Hepatitis B virus strains with an A1757 and are common in genotype D.
The Journal of general virology - 1 Sept 2005
Sendi Hossein, Mehrab-Mohseni Marjan, Zali Mohammad R, Norder Helene, Magnius Lars O
Abstract excerpt
To investigate the role of pre-core and basal core promoter (BCP) mutants in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (e-CHB) in Iran, Hepatitis B virus strains from 30 patients and 42 anti-HBe-positive asymptomatic carriers (ASCs) were characterized. G1896A pre-core stop mutants, detected in 77 % of e-CHB patients and 85 % of ASCs, showed no association with virus load or aminotransferase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
