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Article

Frequency and clinical significance of core promoter and precore region mutations in Tunisian patients infected chronically with hepatitis B.

Journal of medical virology - 1 Nov 2012

Ouneissa Rim, Bahri Olfa, Alaya-Bouafif Nissaf Ben, Chouaieb Sofiene, Ben Yahia Ahlem, Sadraoui Amel, Hammami Walid, Filali Noureddine, Azzouz Mohamed Msaddak, Mami Nabyl Ben, Triki Henda

Abstract excerpt

Genetic variability of hepatitis B virus (HBV) in the C gene and its association with the different stages of chronic liver disease has been studied inadequately with controversial results. The objectives of the current study were to determine the frequency of core promoter and precore mutations in chronic hepatitis B in Tunisia and to evaluate their impact on viral replication and disease progression. Sequencing...

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Share to Disease Progression
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B Core Antigens

Share to Hepatitis B virus

Share to Promoter Regions, Genetic

Share to Tunisia

Share to Virus Replication

Source

Identifiers

PMID: 22997074
DOI: 10.1002/jmv.23394

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