Article
Genome-wide significant localization for working and spatial memory: Identifying genes for psychosis using models of cognition.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2014
Knowles Emma E M, Carless Melanie A, de Almeida Marcio A A, Curran Joanne E, McKay D Reese, Sprooten Emma, Dyer Thomas D, Göring Harald H, Olvera Rene, Fox Peter, Almasy Laura, Duggirala Ravi, Kent Jack W, Blangero John, Glahn David C
Abstract excerpt
It is well established that risk for developing psychosis is largely mediated by the influence of genes, but identifying precisely which genes underlie that risk has been problematic. Focusing on endophenotypes, rather than illness risk, is one solution to this problem. Impaired cognition is a well-established endophenotype of psychosis. Here we aimed to characterize the genetic architecture of cognition using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
