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Article

Genome-wide strategies for discovering genetic influences on cognition and cognitive disorders: methodological considerations.

Cognitive neuropsychiatry - 1 Jan 2009

Potkin Steven G, Turner Jessica A, Guffanti Guia, Lakatos Anita, Torri Federica, Keator David B, Macciardi Fabio

Abstract excerpt

INTRODUCTION: Genes play a well-documented role in determining normal cognitive function. This paper focuses on reviewing strategies for the identification of common genetic variation in genes that modulate normal and abnormal cognition with a genome-wide association scan (GWAS). GWASs make it possible to survey the entire genome to discover important but unanticipated genetic influences. METHODS: The use of a...

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Identifiers

PMID: 19634037
DOI: 10.1080/13546800903059829
PMCID: PMC3037334

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