Article
Association among 1267 A/G HSP70-2, -308 G/A TNF-α polymorphisms and pro-inflammatory plasma mediators in old ZincAge population.
Biogerontology - 1 Feb 2014
Giacconi R, Costarelli L, Malavolta M, Piacenza F, Galeazzi R, Gasparini N, Basso A, Mariani E, Fulop T, Rink L, Dedoussis G, Kanoni S, Herbein G, Jajte J, Busco F, Mocchegiani E
Abstract excerpt
Proinflammatory cytokines and heat shock proteins play relevant roles in the pathogenesis of inflammatory diseases. We investigated whether Hsp70 1267 A/G and TNF-α -308 G/A polymorphisms are associated with proinflammatory mediators, zinc status and laboratory parameters in 1,078 healthy elderly from ZincAge study. Hsp70 1267 A/G genotype and allele distribution were similar among various European countries,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.