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Article

Heat shock protein 70-2+1267 AA homozygotes have an increased risk of septic shock in adults with community-acquired pneumonia.

Critical care medicine - 1 May 2003

Waterer Grant W, ElBahlawan Lama, Quasney Michael W, Zhang Qing, Kessler Lori A, Wunderink Richard G

Abstract excerpt

OBJECTIVE: Heat shock protein (HSP)70-2 is an important immunomodulatory protein induced in response to inflammatory stimuli. We assessed whether HSP70-2+1267 genotype influenced the risk of septic shock in a prospective cohort study of community-acquired pneumonia and whether HSP70-2+1267 genotype is a better predictor of septic shock than the genotype at lymphotoxin-alpha +250. DESIGN: Prospective cohort study....

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Identifiers

PMID: 12771604
DOI: 10.1097/01.CCM.0000063088.86079.03

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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