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Variations in Virulence and Molecular Biology among Emerging Strains of Clostridium difficile

1 Dec 2013

Abstract excerpt

Clostridium difficile is a Gram-positive, spore-forming organism which infects and colonizes the large intestine, produces potent toxins, triggers inflammation, and causes significant systemic complications. Treating C. difficile infection (CDI) has always been difficult, because the disease is both caused and resolved by antibiotic treatment. For three and a half decades, C. difficile has presented a treatment...

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PMID: 24296572
DOI: 10.1128/mmbr.00017-13

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