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Comparison of toxin and spore production in clinically relevant strains of Clostridium difficile

18 Feb 2011

Abstract excerpt

Clostridium difficile is a major cause of nosocomial diarrhoea. The toxins that it produces (TcdA and TcdB) are responsible for the characteristic pathology of C. difficile infection (CDI), while its spores persist in the environment, causing its widespread transmission. Many different strains of C. difficile exist worldwide and the epidemiology of the strains is ever-changing: in Scotland, PCR ribotype 012 was...

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PMID: 21330434
DOI: 10.1099/mic.0.046243-0

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