Article
Regional replication of association with refractive error on 15q14 and 15q25 in the Age-Related Eye Disease Study cohort.
Molecular vision - 1 Jan 2013
Simpson Claire L, Wojciechowski Robert, Yee Stephanie S, Soni Poorva, Bailey-Wilson Joan E, Stambolian Dwight
Abstract excerpt
PURPOSE: Refractive error is a complex trait with multiple genetic and environmental risk factors, and is the most common cause of preventable blindness worldwide. The common nature of the trait suggests the presence of many genetic factors that individually may have modest effects. To achieve an adequate sample size to detect these common variants, large, international collaborations have formed. These consortia...
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