Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Type III TGF-Î² receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma

14 Oct 2013

Abstract excerpt

Growth factors and their receptors coordinate neuronal differentiation during development, yet their roles in the pediatric tumor neuroblastoma remain unclear. Comparison of mRNA from benign neuroblastic tumors and neuroblastomas revealed that expression of the type III TGF-β receptor (TGFBR3) decreases with advancing stage of neuroblastoma and this loss correlates with a poorer prognosis. Patients with MYCN...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Neuroblastoma Research and Treatments
Share to Neuroendocrine Tumor Research Advances

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24216509
DOI: 10.1172/jci69657

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Type III TGF-Î² receptor promotes FGF2-mediated neuronal differentiation in neuroblastomaPMID 24216509Read ↗

Increased TGFbeta type II receptor expression suppresses the malignant phenotype and induces differentiation of human neuroblastoma cells.Semantic proximity Read ↗

Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.Semantic proximity Read ↗

A mechanism linking Id2-TGFβ crosstalk to reversible adaptive plasticity in neuroblastoma.Semantic proximity Read ↗

The RUNX Family Defines Trk Phenotype and Aggressiveness of Human Neuroblastoma through Regulation of p53 and MYCN.Semantic proximity Read ↗

Trk Receptor Expression and Inhibition in NeuroblastomasSemantic proximity Read ↗

The Extracellular Matrix and Neuroblastoma Cell Communication—A Complex Interplay and Its Therapeutic ImplicationsSemantic proximity Read ↗

Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes.Semantic proximity Read ↗

Clinical significance of <i>NTRK</i> family gene expression in neuroblastomasSemantic proximity Read ↗

FGFR1 is a potential therapeutic target in neuroblastomaSemantic proximity Read ↗

TWIST1 expression is associated with high-risk neuroblastoma and promotes primary and metastatic tumor growthSemantic proximity Read ↗

Nedd4-Binding Protein 1 and TNFAIP3-Interacting Protein 1 Control MHC-1 Display in NeuroblastomaSemantic proximity Read ↗

NR2F6 promotes the malignant progression of neuroblastoma as an indicator of poor prognosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.