Article

NR2F6 promotes the malignant progression of neuroblastoma as an indicator of poor prognosis

2023-09-15

Abstract excerpt

<h4>Background: </h4> NR2F6 is an orphan nuclear receptor with dual tumorigenic activity in the immune system and tumor cells, playing an essential role in tumor differentiation and immunity. This study aimed to investigate the expression level of NR2F6 in various tumors and its effect on neuroblastoma. Methods We evaluated the role of NR2F6 in the genesis and development of 34 different tumors through multiple d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4af86490-aeaa-5c55-bdef-9f6e1df4216f
DOI: 10.21203/rs.3.rs-3346890/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

NR2F6 promotes the malignant progression of neuroblastoma as an indicator of poor prognosisDOI 10.21203/rs.3.rs-3346890/v1Read

Insights into the emerging immune checkpoint NR2F6 in cancer immunitySemantic proximity Read

Long non-coding RNA NR2F1-AS1 promoted neuroblastoma progression through miR-493-5p/TRIM2 axis.Semantic proximity Read

Melanoma-intrinsic NR2F6 activity regulates anti-tumor immunitySemantic proximity Read

m6A reader YTHDF1 inhibits the growth of neuroblastoma in vitro and in vivoSemantic proximity Read

Revisiting Neuroblastoma: Nrf2, NF-κB and Phox2B as a Promising Network in NeuroblastomaSemantic proximity Read

Bioinformatics identification of key genes associated with risk and prognosis of neuroblastomaSemantic proximity Read

The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation.Semantic proximity Read

Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockadeSemantic proximity Read

Molecular targeting therapies for neuroblastoma: Progress and challengesSemantic proximity Read

The role of ncRNAs in neuroblastoma: mechanisms, biomarkers and therapeutic targetsSemantic proximity Read

Comprehensive Analysis and Validation Reveal Potential MYCN Regulatory Biomarkers Associated with Prognosis of NeuroblastomaSemantic proximity Read

Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting metastasisSemantic proximity Read