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Article

Genetic variations in cancer-related significantly mutated genes and lung cancer susceptibility.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jul 2017

Zhang Y, Zhang L, Li R, Chang D W, Ye Y, Minna J D, Roth J A, Han B, Wu X

Abstract excerpt

BACKGROUND: Cancer initiation and development are driven by key mutations in driver genes. Applying high-throughput sequencing technologies and bioinformatic analyses, The Cancer Genome Atlas (TCGA) project has identified panels of somatic mutations that contributed to the etiology of various cancers. However, there are few studies investigating the germline genetic variations in these significantly mutated genes...

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Identifiers

PMID: 28383694
DOI: 10.1093/annonc/mdx161
PMCID: PMC5834153

Genes

ATR
ERBB4
SETBP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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