Article
Lung Adenocarcinoma With MUC4 Expression Is Associated With Smoking Status, HER2 Protein Expression, and Poor Prognosis: Clinicopathologic Analysis of 338 Cases.
Clinical lung cancer - 1 Jul 2017
Rokutan-Kurata Mariyo, Yoshizawa Akihiko, Sumiyoshi Shinji, Sonobe Makoto, Menju Toshi, Momose Masanobu, Koyama Mizuki, Shigeto Shohei, Fujimoto Masakazu, Zhang Meng, Morita Satoshi, Date Hiroshi, Haga Hironori
Abstract excerpt
BACKGROUND: MUC4 is a transmembrane glycoprotein that plays a role in the cell growth signaling pathway and has been studied in various organ malignancies. This study aimed to analyze MUC4 expression in resected lung adenocarcinomas (ADCs) to define the clinicopathologic characteristics of MUC4-positive cancers. PATIENTS AND METHODS: Immunohistochemical MUC4 analysis was performed using tissue microarray slides...
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