The influence of ERAP1 gene variants on clinical phenotype in ankylosing spondylitis.

doi:10.3109/03009742.2016.1150507

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The influence of ERAP1 gene variants on clinical phenotype in ankylosing spondylitis.

Scandinavian journal of rheumatology - 1 Nov 2016

Nossent J C, Johnsen S, Bakland G

Abstract excerpt

OBJECTIVES: Endoplasmic reticulum aminopeptidase 1 (ERAP1) gene variants diminish the risk of developing ankylosing spondylitis (AS) through a reduction in ERAP1 activity. We investigated whether disease expression was altered in patients who developed AS despite the presence of two protective ERAP1 variants. METHOD: We conducted a cross-sectional and longitudinal cohort study of patients with established AS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aminopeptidases
Share to Case-Control Studies
Share to Interleukin-6
Share to Minor Histocompatibility Antigens

Source

Open in PubMed

Identifiers

PMID: 27095091
DOI: 10.3109/03009742.2016.1150507

Genes

ERAP1
TNF
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Share to Spondylitis, Ankylosing

Share to Tumor Necrosis Factor-alpha