Article
TLR-8, TNF-α, and ESR-1α Gene Polymorphism Susceptibility in Onset of Arthritis.
Genetics research - 1 Jan 2022
Mukhtar Maryam, Sheikh Nadeem, Batool Andleeb, Saleem Tayyaba, Khawar Muhammad Babar, Irfan Mavra, Suqaina Saira Kainat
Abstract excerpt
Arthritis is a genetic disorder characterized by bones and joint degradation assisted by severe pain and inflammation. It is evident by the studies that 0 candidate genes variations play vital role in its development and progression. Therefore, we investigated the genetic variation of TLR-8, TNF, and ESR-1α genes in the Pakistani population. A case-control study comprising 300 RA, 316 OA, and 412 control subjects...
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