Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset.

PloS one - 1 Jan 2011

Chibnik Lori B, Keenan Brendan T, Cui Jing, Liao Katherine P, Costenbader Karen H, Plenge Robert M, Karlson Elizabeth W

Abstract excerpt

BACKGROUND: Cumulative genetic profiles can help identify individuals at high-risk for developing RA. We examined the impact of 39 validated genetic risk alleles on the risk of RA phenotypes characterized by serologic and erosive status. METHODS/PRINCIPAL FINDINGS: We evaluated single nucleotide polymorphisms at 31 validated RA risk loci and 8 Human Leukocyte Antigen alleles among 542 Caucasian RA cases and 551...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Health

Share to Odds Ratio

Share to Risk Factors

Share to ROC Curve

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 21931699
DOI: 10.1371/journal.pone.0024380
PMCID: PMC3171415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset.PMID 21931699Read ↗

Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk.Semantic proximity Read ↗

The genetic puzzle of rheumatoid arthritis: Causes, progression, and treatmentSemantic proximity Read ↗

Improved performance of epidemiologic and genetic risk models for rheumatoid arthritis serologic phenotypes using family history.Semantic proximity Read ↗

Genetics of rheumatoid arthritis susceptibility, severity, and treatment response.Semantic proximity Read ↗

Clinical usefulness of genetic information for predicting radiographic damage in rheumatoid arthritis.Semantic proximity Read ↗

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.Semantic proximity Read ↗

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis.Semantic proximity Read ↗

Uncovering specific genetic-respiratory disease endotypes for rheumatoid arthritis risk.Semantic proximity Read ↗

The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA.Semantic proximity Read ↗

Association of environmental and genetic factors and gene-environment interactions with risk of developing rheumatoid arthritis.Semantic proximity Read ↗

Genetic influences modulating the radiological severity of rheumatoid arthritis.Semantic proximity Read ↗

Do Genetic Susceptibility Variants Associate with Disease Severity in Early Active Rheumatoid Arthritis?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.