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Article

Allele *2 of the HS1,2A enhancer of the Ig regulatory region associates with rheumatoid arthritis.

Annals of the rheumatic diseases - 1 Mar 2009

Tolusso B, Frezza D, Mattioli C, Fedele A L, Bosello S, Faustini F, Peluso G, Giambra V, Pietrapertosa D, Morelli A, Gremese E, De Santis M, Ferraccioli G F

Abstract excerpt

OBJECTIVE: To investigate the role of the HS1,2 enhancer polymorphisms as a new candidate marker for rheumatoid arthritis (RA) and to define the possible association with autoantibody positivity and clinical outcome. METHODS: Genomic DNA was obtained from two cohorts of patients with RA (100 with...

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Share to Antirheumatic Agents
Share to Arthritis, Rheumatoid
Share to Autoantibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

Share to Immunoglobulin Heavy Chains

Share to Regulatory Sequences, Nucleic Acid

Share to Rheumatoid Factor

Share to Severity of Illness Index

Source

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Identifiers

PMID: 18952640
DOI: 10.1136/ard.2008.095414
PMCID: PMC2633630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18952640-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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