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Article

Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patients.

Arthritis and rheumatism - 1 Feb 2004

Gorman Jennifer D, Lum Raymond F, Chen John J, Suarez-Almazor Maria E, Thomson Glenys, Criswell Lindsey A

Abstract excerpt

OBJECTIVE: The strongest known genetic association in rheumatoid arthritis (RA) is with HLA-DRB1 alleles that share a similar amino acid sequence, termed the shared epitope (SE). Although many studies have examined the association of the SE with disease severity, the results have been inconsistent, which may reflect the relatively small sample sizes or ethnic differences. The aim of this study was to assess the...

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Share to Arthritis, Rheumatoid
Share to Epitopes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Histocompatibility Testing

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Population Groups

Source

Identifiers

PMID: 14872482
DOI: 10.1002/art.20006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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