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Article

CYP2C19-rs4986893 confers risk to major depressive disorder and bipolar disorder in the Han Chinese population whereas ABCB1-rs1045642 acts as a protective factor.

BMC psychiatry - 25 Jan 2023

Zhang Ting, Rao Qingmin, Lin Kangguang, He Yongyin, Cai Jintai, Yang Mengxin, Xu Ying, Hou Le, Lin Yulong, Liu Haiying

Abstract excerpt

BACKGROUND: Genetic risks may predispose individuals to major mood disorders differently. This study investigated the gene polymorphisms of previously reported candidate genes for major depressive disorder (MDD) and bipolar disorder (BPD) in the Han Chinese population. METHODS: Twenty loci of 13 candidate genes were detected by MALDI-TOF mass spectrometry in 439 patients with MDD, 600 patients with BPD, and 464...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C19

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Identifiers

PMID: 36698099
DOI: 10.1186/s12888-022-04514-w
PMCID: PMC9875448

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