Article
G protein-coupled receptors as promising cancer targets.
Cancer letters - 1 Jul 2016
Liu Ying, An Su, Ward Richard, Yang Yang, Guo Xiao-Xi, Li Wei, Xu Tian-Rui
Abstract excerpt
G protein-coupled receptors (GPCRs) regulate an array of fundamental biological processes, such as growth, metabolism and homeostasis. Specifically, GPCRs are involved in cancer initiation and progression. However, compared with the involvement of the epidermal growth factor receptor in cancer, that of GPCRs have been largely ignored. Recent findings have implicated many GPCRs in tumorigenesis, tumor progression,...
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