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Genome‐wide DNA methylation profiling identifies a folate‐sensitive region of differential methylation upstream of <i>ZFP57</i> ‐imprinting regulator in humans

2 Jun 2014

Abstract excerpt

Folate intake during pregnancy may affect the regulation of DNA methylation during fetal development. The genomic regions in the offspring that may be sensitive to folate exposure during in utero development have not been characterized. Using genome‐scale profiling, we investigated DNA methylation in 2 immune cell types (CD4 + and antigen‐presenting cells) isolated from neonatal cord blood, selected on the basis...

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PMID: 24891518
DOI: 10.1096/fj.13-249029

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