Article
Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength
28 Jun 2019
Abstract excerpt
Hand grip strength is a measure of muscular strength and is used to study age-related loss of physical capacity. In order to explore the biological mechanisms that influence hand grip strength variation, an epigenome-wide association study (EWAS) of hand grip strength in 672 middle-aged and elderly monozygotic twins (age 55-90 years) was performed, using both individual and twin pair level analyses, the latter...
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